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Table 5 Association of SUA and cardiovascular mortality via Cox regression analysis

From: Gender differences in the relationship between serum uric acid and the long-term prognosis in heart failure: a nationwide study

 

Non-adjusted model

Adjusted model

 

HR (95% CI)

p value

HR (95% CI)

p value

Whole population (N=1593)

    

Continuous per 1 unit increase

1.19 (1.13-1.25)

<0.001

1.12 (1.05-1.19)

<0.001

Tertile 1 (<5.5 mg/dL)

Reference

--

Reference

--

Tertile 2 (5.5-7.0 mg/dL)

0.88 (0.67-1.16)

0.365

0.84 (0.64-1.11)

0.225

Tertile 3 (>7.0 mg/dL)

1.58 (1.24-2.02)

<0.001

1.27 (0.96-1.68)

0.097

Men (N=897, 56.3%)

    

Continuous per 1 unit increase

1.21 (1.13-1.29)

<0.001

1.18 (1.09-1.28)

<0.001

Tertile 1 (<5.9 mg/dL)

Reference

--

Reference

--

Tertile 2 (5.9-7.4 mg/dL)

0.92 (0.64-1.32)

0.645

0.96 (0.65-1.40)

0.817

Tertile 3 (>7.4 mg/dL)

2.02 (1.46-2.81)

<0.001

1.76 (1.21-2.57)

0.003

Women (N=696, 43.7%)

    

Continuous per 1 unit increase

1.15 (1.06-1.26)

0.001

1.01 (0.91-1.12)

0.902

Tertile 1 (<5.1 mg/dL)

Reference

--

Reference

--

Tertile 2 (5.1-6.5 mg/dL)

1.19 (0.80-1.77)

0.387

0.80 (0.52-1.22)

0.300

Tertile 3 (>6.5 mg/dL)

1.47 (0.99-2.17)

0.053

0.77 (0.49-1.20)

0.248

  1. The multivariate Cox regression analysis was adjusted for age, race, stroke, BMI, diastolic BP, hemoglobin, triglyceride, albumin, eGFR, serum sodium, serum potassium, serum chloride, prescription of beta-blockers, prescription of MRA, prescription of diuretics, and prescription of urate-lowering agents
  2. Abbreviation: BMI, body mass index; BP, blood pressure, eGFR, the rate of estimated glomerular filtration rate; MRA, mineralocorticoid-receptor antagonist; HR, hazard ratio; CI, confidence interval