Table 2 Baseline demographic and clinical characteristics in women

Uric acid (mg/dL)

5.9 (4.8-7.1)

<5.1

5.1-6.5

>6.5

Age, years

71 (60-80)

66 (51-78)

71 (61-80) ^†

74 (64-80) ^†

Body mass index, kg/m²

30.6 (25.9-37.8)

28.6 (25.1-34.0)

31.8 (26.2-37.9) ^†

31.7 (27.3-40.3) ^†

Systolic BP, mmHg

134 (118-150)

134 (118-148)

136 (119-152)

132 (116-146)

Diastolic BP, mmHg

65 (56-74)

66 (58-74)

66 (58-76)

64 (54-72) ^{† ‡}

Heart rate, bpm

70 (62-80)

70 (64-80)

70 (62-78)

72 (62-80)

Race, n (%)

Non-Hispanic White

348 (50.0)

113 (50.7)

114 (48.5)

121 (50.8)

No-Hispanic Black

188 (27.0)

49 (22.0)

63 (26.8)

76 (31.9) ^†

Mexican American

81 (11.6)

32 (14.3)

35 (14.9)

14 (5.9) ^†‡

Other

79 (11.4)

29 (13.0)

23 (9.8)

27 (11.4)

History of smoking, n (%)

333 (47.8)

104 (46.6)

122 (51.9)

107 (45.0)

History of drinking, n (%)

306 (44.0)

100 (44.8)

109 (46.4)

97 (40.8)

Hypertension, n (%)

594 (85.3)

178 (79.8)

206 (87.7) ^†

210 (88.2) ^†

Diabetes mellitus, n (%)

312 (44.8)

90 (40.4)

95 (40.4)

127 (53.4) ^†‡

Coronary heart disease, n (%)

209 (30.0)

69 (30.9)

69 (29.4)

71 (29.8)

Stroke, n (%)

148 (21.3)

52 (23.3)

44 (18.7)

52 (21.8)

Laboratory tests

WBC, 10³/uL

7.2 (5.9-8.8)

7.1 (5.9-8.4)

7.1 (5.9-9.0)

7.4 (6.1-8.8)

Hemoglobin, g/dL

12.7 (11.4-13.7)

12.9 (11.4-13.7)

12.9 (11.9-13.9)

12.3 (11.3-13.5) ^{† ‡}

Albumin, g/L

40.0 (38.0-42.0)

40.0 (38.0-42.0)

40.0 (38.0-42.0)

40.0 (38.0-42.0)

HbA1c, %

5.9 (5.5-6.7)

5.8 (5.4-6.5)

5.9 (5.6-6.6) ^†

6.1 (5.6-7.1) ^{† ‡}

Total cholesterol, mmol/L

4.8 (4.0-5.6)

4.9 (3.9-5.8)

5.0 (4.2-5.8)

4.6 (3.8-5.3) ^‡

Triglyceride, mg/dL

135.0 (95.0-195.0)

122.0 (82.0-186.0)

141.0 (102.0-194.0) ^†

137.5 (104.0-202.5) ^†

Serum glucose, mg/dL

102.0 (91.3-129.0)

99.0 (88.0-120.0)

100.0 (90.0-123.0)

107.0 (94.0-140.3) ^{† ‡}

eGFR, mL/min/1.73m²

77.1 (49.7-99.9)

94.1 (69.9-109.8)

79.3 (59.6-98.4) ^†

53.9 (36.7-81.4) ^{† ‡}

Serum sodium, mmol/L

139.0 (137.9-141.0)

139.0 (137.0-141.0)

140.0 (138.0-142.0) ^†

139.6 (138.0-141.8) ^†

Serum potassium, mmol/L

4.1 (3.8-4.4)

4.0 (3.7-4.3)

4.1 (3.8-4.3) ^†

4.2 (3.9-4.5) ^†

Serum chloride, mmol/L

102.0 (100.0-105.0)

102.0 (99.0-105.0)

103.0 (100.0-105.0)

102.0 (100.0-105.0)

Medication

ACEI/ARB, n (%)

373 (53.6)

103 (46.2)

134 (57.0) ^†

136 (57.1) ^†

Beta blockers, n (%)

357 (51.3)

91 (40.8)

125 (53.2) ^†

141 (59.2) ^†

MRA, n (%)

62 (8.9)

9 (4.0)

20 (8.5) ^†

33 (13.9) ^†

Diuretics, n (%)

378 (54.3)

81 (36.3)

121 (51.5) ^†

176 (73.9) ^†‡

Urate-lowering agents, n (%)

28 (4.0)

10 (4.5)

6 (2.6)

12 (5.0)